Description
What Is an Ampoule Drawing Filling and Sealing Machine?
An ampoule drawing filling and sealing machine is special pharmaceutical equipment for glass ampoules. It combines liquid filling, nitrogen purging and wire drawing fusion sealing into one complete working flow.
After accurate liquid filling, open
flame heats the ampoule neck. The equipment stretches the heated glass to form a tight sealed tip. This solid seal effectively stops liquid contamination and oxidation.
Boasting a compact body and steady running performance, the machine fits labs, research institutes and small-scale production lines perfectly. It works with all glass ampoules ranging from 1 ml to 20 ml.
How to Operate the Machine
- Link oxygen, fuel gas and nitrogen pipelines to the rear interfaces of the machine. Turn on the gas pressure regulator and light the flame. Slowly adjust the oxygen valve until a blue flame forms with a 5–8 mm flame core.
- Follow the automatic working sequence: manual bottle feeding → pre-nitrogen flushing → liquid filling → post-nitrogen flushing → automatic sealing → manual finished product collection.
- Sealing duration changes with flame size and heat intensity. Most ampoule mouths take 2 to 3 seconds to melt and seal fully.

Core Product Features
Touch Screen HMI with Peristaltic Pump Filling
A touch-screen human-machine interface allows one-click filling volume adjustment. Peristaltic pump filling delivers precise dosing without liquid dripping.
Electronic Sensor-Controlled Nitrogen Purging
A photoelectric sensing nitrogen flushing system activates a no-bottle-no-filling function, boosting overall production safety and efficiency.

Side-Insert Filling Design Against Splashing
Side-spray filling needles insert into ampoules to prevent liquid splashes and avoid bulges on sealed tips. Both filling and nitrogen needles adopt 316L stainless steel as manufacturing material.

Quick Size Switch for 1–20 ml Ampoules
Fast component replacement adapts the machine to all 1–20 ml ampoule specifications, meeting diverse laboratory and trial production demands.
High-Precision Gas Flow Regulation
High-accuracy flow valves maintain consistent, stable gas output during nitrogen purging and flame sealing steps.

Dual Optional Gas Supply Modes
Two gas combinations are available: LPG plus oxygen, or hydrogen-oxygen mixed gas. Different site safety standards and production needs can be fully satisfied.

Real Product Photos

Pre-Delivery Test Video
Every desktop ampoule filling and sealing machine undergoes full comprehensive inspection before shipment. Complete installation and functional verification videos get recorded in line with standardized testing procedures.
Tests run under real simulated production conditions. Full working procedures including ampoule feeding, liquid filling, flame sealing, wire drawing and finished product separation are completed during each trial. Key performance metrics get measured strictly, covering filling precision, sealing uniformity, flame stability, positioning accuracy, smooth operation and glass ampoule integrity.
Rigorous quality control ensures every compact automatic ampoule filling and sealing machine meets pharmaceutical-grade standards and maintains stable long-term working efficiency for hospitals, laboratories, small pharmaceutical factories and biotechnology enterprises.
Technical Parameters
| Item |
Specification |
| Model |
YH-APSM2S |
| Power Supply |
AC 220V / 50Hz / 200W |
| Applicable Container |
1–20 ml glass ampoules (rotary disc replacement for different sizes) |
| Control System |
PLC + touchscreen; adjustable filling volume; multi-language support (Chinese, English, etc.) |
| Main Motor Speed |
1350 r/min |
| Rotary Bottle Motor Speed |
100 r/min |
| Filling Needle Material |
316L stainless steel |
| Sealing Method |
Wire Drawing Fusion Sealing |
| Nitrogen Filling Stations |
Pre-filling nitrogen, post-filling nitrogen, nitrogen filling during sealing |
| Burner Head Quantity |
2 pieces |
| Supported Gas Types |
HHO hydrogen-oxygen gas or LPG + oxygen |
| Production Output |
≥ 20 ampoules per minute |
| Machine Weight |
Approx. 90 kg |
| Overall Dimensions (L×W×H) |
900670800 mm |
Model Comparison Table
| Item |
YH-APSM2S |
YH-APSM2 |
AGL-2 |
| Power Supply |
AC 220V / 50Hz / 200W |
AC 220V / 50Hz / 200W |
220V / 50Hz / 370W |
| Applicable Ampoules |
1–20 ml |
1–20 ml |
1–2 ml |
| Hourly Production Capacity |
≥ 1200 pieces |
≥ 1200 pieces |
2400–3600 pieces |
| Burner Head Quantity |
2 |
2 |
2 |
| Control System |
PLC touch screen |
PLC touch screen |
Equipped |
| Sealing Method |
Wire Drawing Fusion Sealing |
Blow Sweep Residue-Free Sealing Head |
Wire Drawing Fusion Sealing |
| Adjustable Filling Volume |
✔ |
✔ |
× |
| Equipped Flow Meter |
✔ |
✔ |
✔ |
| Number of Filling Needles |
1 |
1 |
2 |
| 316L Stainless Steel Filling Needles |
✔ |
✔ |
✔ |
| Waste Ampoule Tip Collection |
YES |
No |
YES |
| Front & Rear Dual Nitrogen Filling |
✔ |
✔ |
✔ |
| Compatible with HHO / LPG+Oxygen |
✔ |
✔ |
✔ |
| Machine Weight |
Approx. 90 kg |
65 kg |
75–85 kg |
| Overall Dimensions (L×W×H) |
900670800 mm |
660550500 mm |
10007501000 mm |
Frequently Asked Questions
- How is machine quality guaranteed?
- What is the price of this equipment?
- What quality assurance measures apply after order confirmation?
- What installation guidance and after-sales support come with the machine?
Packing & Shipping

Summary
This integrated desktop ampoule drawing filling and sealing machine combines filling, nitrogen protection and flame sealing within a compact framework. Flexible ampoule size compatibility, precise control systems and dual gas supply options make it ideal for laboratory trials and small-batch pharmaceutical manufacturing. Every unit passes strict full testing before delivery to sustain consistent reliable performance. Simple operation and complete after-sales services further make it a practical choice for research labs, biotech companies and small drug manufacturers.
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