Description
What Is a Pharmaceutical Vial Filling Machine
A pharmaceutical vial filling, stoppering and capping machine is a compact fully automatic unit. It measures liquid medicine accurately and fills the liquid into glass or plastic vials. The machine then fits rubber stoppers and crimps aluminum caps automatically without extra manual work.
This bench-top model combines precise liquid filling, rubber stoppering and cap sealing into one reliable stoppering and capping machine integrated device. It suits lab research, new drug development, pilot trials and small-batch packaging perfectly.
Pharmaceutical, biotech, medical and fine chemical sectors widely adopt this equipment. It delivers consistent filling results, cuts raw material waste and maintains high efficiency for research and small-scale manufacturing.
How the Automatic Vial Filling and Capping Machine Works
Users set all operation parameters of this stoppering and capping machine on the PLC touch screen in advance before starting production. Once all data is confirmed, the whole production sequence of the stoppering and capping machine runs fully automatically afterward, following these orderly steps:
1.Automatic feeding of clean empty vials into the working station
2.Intelligent photoelectric detection (filling stops instantly when no vial is detected to avoid waste)
3.Stable high-precision liquid filling with controllable volume
4.Complete stoppering process (half stoppering or full stoppering optional based on lyophilization demands)
5.Tight aluminum cap crimping and airtight sealing finished by the stoppering and capping machine
A flexible manual operation mode stays available on this stoppering and capping machine for routine equipment testing and precise calibration. Multiple interchangeable fittings come with the machine to support diverse batch production requirements. The independent segmented control system separately manages filling, stoppering and capping stations of the stoppering and capping machine, which perfectly caters to standard lyophilization production workflows.
Working Process Matched for Freeze-Drying
YHGZ-20 features a modular split workflow built for freeze-drying applications. Every functional station can activate or pause separately via the touch screen.
- Vial feeding
Empty vials travel into the machine through an automatic feeding track.
- Liquid filling
Filling starts right after bottle positioning. Built-in anti-drip structures prevent liquid waste and dripping.
- Stoppering station (pre-freeze-dry half sealing)
Rubber stoppers get pressed into vials automatically. Half stoppering mode creates tiny gaps inside bottles to support gas exchange during freeze-drying.
- Process pause and tray unloading
Production can halt once stoppering finishes. Vials are taken out and transferred to lyophilizers for freeze-drying treatment.
- Post-freeze-drying capping (final tight sealing)
Vials return to the machine after freeze-drying. The unit crimps aluminum caps to form complete airtight sealing.
Every single working stage can be turned on or off on the touch screen. Such flexible control fits formulas of various medical products.
Key Features of the Vial Filling Machine
Real Detail Pictures
Custom Upgrade: Class 100 Laminar Flow Hood
Introduction to Class 100 Laminar Flow Hood
A Class 100 laminar flow hood acts as a local cleanroom device. It filters air and generates steady laminar airflow to build a dust-free, stable operating zone.
Class 100 standard means the working area contains fewer than 100 particles (≥0.5 μm) per cubic foot of air, which matches ISO Class 5 cleanliness level.
Vertical fully automatic vial filling and capping machines are also available for custom orders.
Equipment Test Video
Complete test footage records for every batch of equipment before shipment. All inspection steps follow unified official standards. Testing simulates real production conditions, including material separation and stripping procedures. Core indicators covering positioning accuracy, running stability and material protection receive full measurement. Strict tests guarantee all delivered machines satisfy quality standards and functional requirements.
Technical Specifications
| Item |
Specification |
| Model |
YHGZ-20 Automatic Vial Filling and Capping Machine |
| Max Single Filling Volume |
Ceramic Pump: 10 ml; Peristaltic Pump: 20 ml |
| Applicable Vial Mouth Size |
13 mm / 20 mm |
| Filling Circulation Speed |
60 cycles/min |
| Production Output |
25–30 bottles/min |
| Working Voltage |
220 V, 50 Hz |
| Capping Type |
Single-blade Crimping |
| Bottle Sorting Motor Power |
120 W |
| Dial Wheel Motor Power |
120 W |
| Vibratory Hopper Size |
200 mm |
| Working Air Pressure |
≤ 0.8 MPa |
| Air Compressor |
Prepared by buyers |
| Total Machine Weight |
160 kg |
| Overall Dimensions |
1235 mm × 985 mm × 750 mm |
Packing and Shipping
Sturdy protective packaging prevents scratches and structural damage during long distance transit. Reliable global shipping services support allinterational order.
Product Summary
The YHGZ-20 automatic vial filling, stoppering and capping machine is a space-saving bench-top device for laboratories and small pharmaceutical workshops. It unites liquid filling, switchable half/full stoppering and aluminum cap crimping into one single unit. Optional ceramic or peristaltic pumps ensure precise liquid dosing, while independent station control fully supports freeze-drying production lines. The intelligent no-vial-no-filling sensor minimizes liquid waste, and an optional Class 100 laminar flow hood meets high-standard clean manufacturing rules. With intuitive touch screen operation, multi-language interface and long-term stable performance, this model provides an affordable, user-friendly solution for drug research, pilot manufacturing and small-batch vial packaging.
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