Description
A pharmaceutical vial filling, stoppering and capping machine is a compact fully automatic unit. It measures liquid medicine accurately and fills the liquid into glass or plastic vials. The machine then fits rubber stoppers and crimps aluminum caps automatically without extra manual work.
This bench-top model combines precise liquid filling, rubber stoppering and cap sealing into one reliable stoppering and capping machine integrated device. It suits lab research, new drug development, pilot trials and small-batch packaging perfectly.
Pharmaceutical, biotech, medical and fine chemical sectors widely adopt this equipment. It delivers consistent filling results, cuts raw material waste and maintains high efficiency for research and small-scale manufacturing.

How the Automatic Vial Filling and Capping Machine Works

Working Process Matched for Freeze-Drying
- Vial feedingEmpty vials travel into the machine through an automatic feeding track.
- Liquid fillingFilling starts right after bottle positioning. Built-in anti-drip structures prevent liquid waste and dripping.
- Stoppering station (pre-freeze-dry half sealing)Rubber stoppers get pressed into vials automatically. Half stoppering mode creates tiny gaps inside bottles to support gas exchange during freeze-drying.
- Process pause and tray unloadingProduction can halt once stoppering finishes. Vials are taken out and transferred to lyophilizers for freeze-drying treatment.
- Post-freeze-drying capping (final tight sealing)Vials return to the machine after freeze-drying. The unit crimps aluminum caps to form complete airtight sealing.
Key Features of the Vial Filling Machine
- Integrated Automatic System:This machine puts liquid filling, rubber stoppering and cap crimping together in one stable device.
- High Precision Filling:You can choose either a peristaltic pump or ceramic pump. Both deliver exact liquid amounts.
- PLC Control with Touch Screen:You can easily set and adjust parameters to fit different production tasks.
- No Vial, No Filling Function:A photoelectric sensor stops filling when there is no vial. It cuts material waste and makes operation safer.
- Bench-top Structure:This vial filling machine takes up little space. It works great for labs and research groups.
- Multi-language Interface:The system supports Chinese, English and Spanish. We can add other languages on request.
Real Detail Pictures

Custom Upgrade: Class 100 Laminar Flow Hood
Introduction to Class 100 Laminar Flow Hood
A Class 100 laminar flow hood acts as a local cleanroom device. It filters air and generates steady laminar airflow to build a dust-free, stable operating zone.
Class 100 standard means the working area contains fewer than 100 particles (≥0.5 μm) per cubic foot of air, which matches ISO Class 5 cleanliness level.

Equipment Test Video
Technical Specifications
| Item | Specification |
|---|---|
| Model | YHGZ-20 Automatic Vial Filling and Capping Machine |
| Max Single Filling Volume | Ceramic Pump: 10 ml; Peristaltic Pump: 20 ml |
| Applicable Vial Mouth Size | 13 mm / 20 mm |
| Filling Circulation Speed | 60 cycles/min |
| Production Output | 25–30 bottles/min |
| Working Voltage | 220 V, 50 Hz |
| Capping Type | Single-blade Crimping |
| Bottle Sorting Motor Power | 120 W |
| Dial Wheel Motor Power | 120 W |
| Vibratory Hopper Size | 200 mm |
| Working Air Pressure | ≤ 0.8 MPa |
| Air Compressor | Prepared by buyers |
| Total Machine Weight | 160 kg |
| Overall Dimensions | 1235 mm × 985 mm × 750 mm |
Packing and Shipping
Sturdy protective packaging prevents scratches and structural damage during long distance transit. Reliable global shipping services support allinterational order.














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